Endocrine Abstracts

Introduction: Parathyroid carcinoma (PCa) is a rare presentation of primary hyperparathyroidism (PHPT), accounting for less than 1% of cases. Differentiating parathyroid cancer from benign hyperparathyroidism is clinically challenging. Some previous work suggest that there is a paraneoplastic hCG production in parathyroid cancer (Stock et al 1987, Rubin et al 2008). In this study, we aimed to investigate whether the hCG+β kit from Roche Diagnostics could distinguish PCa p...

Introduction: Diabetes is the leading worldwide cause of chronic kidney disease, which is diagnosed by measuring albuminuria and estimating glomerular filtration rate (GFR) with creatinine-based formulas, such as the 2009 CKD-EPI developed in the United States of America (USA). Nonetheless, the race coefficient (RC), present in the 2009 CKD-EPI, may overestimate GFR in other countries.Aim: The goal of this systematic review and meta-analysis was to asses...

Background: Parathyroid carcinoma (PCa) is a rare disease that can be difficult to differentiate initially from benign parathyroid adenoma. PCa over-secrete the amino form of parathyroid hormone (PTH), which is recognized by 3rd generation but not by 2nd generation (‘intact’) PTH assays. In normal individuals, the 3rd generation/2nd generation PTH ratio should always be <1.Material and methods: We studied the utility of the 3rd generation/2...